I have a 4 storey Guest House with 20 radiators. New boiler installed about 2 years ago and Drayton Wiser Hub and Radiator Thermostats, all has worked well until a couple of months ago when 2 or 3 rads stopped heating up. These rads are in our private part of the house, in the basement and the only time they get remotely warm is when i switch all rads on!! Boiler is located in garage on ground floor and motorised valves and HW cylinder is on first floor. I have no idea about the pipe runs as they are all buried in walls but the rads are supplied by copper microbore pipes, i have installed a Magnaclean Pro 2 today on thr Return, next to the boiler and put cleanser into the system. I have trouble shooted the Wiser Rad Thermostats and they are all working properly and even if i take them off the TRV the problem remains the same. All TRVs seem to be OK with the pin moving up and down properly, there anything else i should be doing to try to sort this out please?